[Focused on thin, delicate eye area] PN Booster EndranHiller EYE

Features of EYE Endran

• With patents expiring, a variety of PN skin boosters with similar ingredients are being launched. EYE Endran contains the same PN ingredients and concentration as the original ReXran. This PN is extracted from salmon, making it a suitable choice for those who desire continuous care at a reasonable cost. Since PN extracted from other fish, such as trout, may differ, it is advisable to check if the raw material is salmon-derived.
• From under the eyes, eyelids, and right next to the eye area, customized embossement treatments can be performed by precisely adjusting the depth of the skin layer according to the desired area.
• The PN ingredient is injected in its full 2cc dosage, without dilution with saline solution.
• Its low viscosity can result in less pain during the procedure, and the embossement that appears after injection also tends to subside relatively quickly.
• Because it is designed specifically for the eye area, it can be safely administered even to sensitive areas around the eyes.
• Compared to general PN products, it involves less pain, allowing consideration for full-face treatment as well as the eye area. This can help improve dullness, inner dryness, and fine wrinkles of the skin.
• The medical staff are proficient in pharmacopuncture and injection procedures, allowing for precise drug administration into the dermal layer. After the procedure, we will review the eye area embossement with the patient.

What is EYE Endran (PN) Skin Booster?

EYE Endran is a PN (Polynucleotide) ingredient skin booster developed with a focus on the delicate skin around the eyes.

It is used as a precise treatment that can help alleviate fine wrinkles, dark circles, and inner dryness in the eye area.

It contains the same PN ingredients and concentration as the existing ReXran Healer, but it is specially designed for the thin and sensitive skin around the eyes. Thanks to this, the injection feels smoother, the pain experienced during the procedure is relatively less, and embossement tends to be less pronounced.

Why EYE Endran is Needed for Eye Area Care

The skin around the eyes is the thinnest and most sensitive part of the face.

This thin skin layer easily reacts to external stimuli, and changes due to aging or dryness tend to appear relatively quickly.

In particular, the skin barrier function is prone to weakening, making inner dryness, fine wrinkles, and bluish dark circles commonly appear together.

However, the eye area structurally has less subcutaneous fat and a thin dermal layer, making it difficult to achieve sufficient improvement with general moisturizers or eye creams alone.

For this reason, injecting PN ingredients directly into the dermal layer to induce skin regeneration can be an effective approach.

The Role of PN (Polynucleotide)

PN is a high-purity biological complex derived from salmon DNA.

Compared to the commonly known PDRN, PN has a larger molecular weight and can differ in terms of inducing reactions within the skin's dermal layer and sustaining its effects.

Simply put, while PDRN assists in basic skin hydration and regeneration processes, PN can directly stimulate the dermal layer to contribute to improving skin structure.

PN can help improve skin through mechanisms such as:

It stimulates fibroblasts to promote collagen and elastin production. This can contribute to enhancing skin elasticity, reducing fine wrinkles, and making the skin surface smoother and firmer.

It increases the secretion of various growth factors such as TGF, FGF, and VEGF. This can aid in skin recovery processes and support the regeneration of damaged tissues. Furthermore, it can help calm inflammatory responses and maintain healthy skin conditions.

It induces epidermal cell regeneration and strengthens the skin barrier function. This can strengthen the connections between keratinocytes, reduce water loss, and help improve inner dryness.

Our skin has a barrier-like structure composed of bricks (keratinocytes) and cement (intercellular lipids).

PN can reinforce this cement-like role to prevent moisture evaporation and contribute to improving inner dryness and sensitivity.

It induces the repair of damaged dermal tissue and an increase in thickness. This can reinforce the thinned dermis, helping to alleviate dark circles and improve fine wrinkles.

The skin barrier is composed of bricks called keratinocytes and cement called intercellular lipids. PN strengthens this cement function, reducing water loss, and thereby positively influencing the improvement of inner dryness and skin sensitivity.

Meaning of Embossement and Dermal Layer Injection

The skin's dermal layer is characterized by its narrow structural space.

For this reason, when the medication is injected, a temporary swelling phenomenon may occur.

This phenomenon is called embossement, and it is one of the indicators that the medication has been properly injected into the dermal layer.

After the procedure, we will review and explain the embossement phenomenon with the patient.

Most general PN products can have embossement that lasts for 3-7 days or longer, but EYE Endran has a lower viscosity, so the embossement subsides relatively quickly. Additionally, it involves less pain compared to general PN, allowing for comfortable consideration of treatment even in sensitive areas like the eyes.

Consider This If You Have

• Fine wrinkles around the eyes are a concern
• Recommended for those concerned about bluish dark circles. The bluish appearance of the skin around the eyes is due to the thin dermal layer, which allows blood vessels to show through. EYE Endran can subtly reinforce dermal thickness, helping to improve dark circles.
• Makeup doesn't sit well and skin texture feels rough due to inner dryness
• This treatment may be suitable for those with sensitive or thin skin who have been hesitant about traditional lifting procedures.
• This can be considered if you feel that eye cream alone isn't enough for your eye area concerns.
• Even those who have found it difficult to find a suitable treatment for fine wrinkles on their eyelids can develop an appropriate plan through consultation.
• This treatment can also be considered for those concerned about fine wrinkles around the eyes.

Treatment Cycle and Duration

• Generally, we recommend a total of three treatments, spaced one month apart.
• Thereafter, receiving touch-up treatments approximately every 6 months can help to maintain the effects.
• While individual results may vary, the effects generally last for about 6 months to 1 year.
• The discomfort felt during the procedure may be milder compared to similar treatments, and any post-procedure bumps (embossing) typically subside naturally within 1 to 3 days.

Our Doctor's Perspective

I believe that eye area treatments are important not merely for improving visible wrinkles, but also for focusing on activating the skin's inherent regeneration and recovery capabilities.

Sometimes, the desired improvement in the eye area can be difficult to achieve with just daily eye cream. In these instances, treatments like 'Eye Endran' can be considered to see if they can bring about a different kind of change to the skin.

You might find that surface-level skincare alone isn't enough to fully address your eye area concerns.

In such cases, a procedural approach may be necessary to improve the health and thickness of the skin's deeper layers, particularly the dermis.

From this perspective, Eye Endran can be considered as a first step.

When performing skin procedures, precision and delicacy are essential.

It is crucial to inject the treatment solution into the precise area, carefully monitor every step of the process, and meticulously observe the patient's progress.

Our medical team will treat our patients based on these principles.